An ongoing list of information about this fighting game title from 1995.
Characters
For a majority of these characters this was their first time appearing in a fighting game.
(8 of them which include Spider-Man, Captain America, Shuma-Gorath, Iron Man, Blackheart, Hulk, Doctor Doom, and Thanos)
Spider-Man
First time in a video game where Mary Jane and Peter tease the possibility they could have a baby (maybe 1st time anywhere outside the comics at the time)
Voice Actor: Patrick Chilvers
Magneto
First time in the official roster as a select-able character in a fighting game. (He was select-able via secret input in X-Men Children of the Atom.)
Voice Actor: Lorne Kennedy
Same VA as Doctor Doom and the game announcer in Marvel Super Heroes who also voiced En Sabah Nur in an episode of X-Men the Animated Series.
Captain America
Voice Actor: Cal Dodd
Same VA as Wolverine in MSH and X-Men the Animated Series.
Shuma-Gorath
Shuma's first video game appearance and first time the character was voiced in any type of media.
Only Marvel fighting game where Shuma-Gorath's default color is pink. All the other entries the character appeared in it's start color was green.
Voice Actor: Frank Perry
Psylocke
First game she can Triple Jump in. (In X-Men Children of the Atom she could Double Jump)
First time being able to use the supers Psi-Maelstrom and Kochou Gakure.
Psylocke's last appearance in a Marvel Capcom fighter until MvC2 (where she has her last appearance).
Voice Actor: Catherine Disher
Same VA in X-Men Children of the Atom who also voiced Jean Grey in X-Men the Animated Series.
Wolverine
First time being able to use the Weapon X super in a fighting game.
Voice Actor: Cal Dodd
Same VA as Captain America in Marvel Super Heroes and Wolverine in X-Men the Animated Series.
Blackheart
His first video game appearance and first time he was ever voiced in any type of media.
Voice Actor: Jaimz Woolvett
Iron Man
First time wearing the Modular Suit in a video game.
First time voiced in a video game (If not including the all-encompassing voice-over from Captain America & the Avengers).
First time Tony's shown saving the universe with the Infinity Gauntlet.
Iron Man's infinite remains (mostly) the same from this game to his next appearance in Marvel Vs. Capcom 2.
(The damage scaling is however more restrictive in MvC2)
Voice Actor: Chris Britton
Same VA as Mister Sinister in X-Men the Animated Series.
Juggernaut
First time in the official roster as a select-able character in a fighting game and technically the 2nd time he was ever playable in a video game. (He was select-able via secret input in X-Men Children of the Atom.)
Voice Actor: Rick Bennett
Same VA who voiced Juggernaut and Colossus in X-Men the Animated Series.
Hulk
First time audibly speaking in an arcade game or video game (if you don't count grunts & roars from The Incredible Hulk on Sega/SNES/handhelds).
First appearance of Professor Hulk in a video game.
First time in a video game Hulk had a select-able gray color.
Only Marvel fighting game Hulk has the Gamma Lift projectile. (Rips piece of floor off ground, holds it over head, and can throw it)
Voice Actor: Andrew Jackson
Same VA as Thanos in Marvel Super Heroes.
Doctor Doom
His first playable video game appearance (via special input).
Voice Actor: Lorne Kennedy
Same VA as Magneto and the game announcer in Marvel Super Heroes and voiced En Sabah Nur in an episode of X-Men the Animated Series.
Thanos
His first video game appearance (also as a playable character via secret input).
First time he was ever voiced in any type of media.
First fighting game character to have 6 supers. (Pretty sure.)
Voice Actor: Andrew Jackson
Same VA as Hulk in Marvel Super Heroes.
Anita
First time she was a playable character by herself.
First crossover of a playable Darkstalker character in another video game's title.
First appearance of a Darkstalker character in a Marvel title.
Summons Mei-Ling which is technically the 2nd appearance of a Darkstalker character in a Marvel title.
One of her moves summons Akuma which marks his 2nd appearance in a Marvel fighting game. (First was as a secret playable character in X-Men Children of the Atom)
Only character in the game to have a Quadruple Jump (and probably the first time in a fighting game a character had one / need to confirm)
Anita was somewhat of an "incomplete character" at the time and being a secret character on Japanese hardware. She was added to later installments (MvC Origins and Arcade1Up)
Cameos
First appearance of Mephisto's monstrous form in a video game.
First appearance of Drax in a video game.
First appearance of Nova in a video game.
First appearance of (Marvel's) Death in a video game.
First appearance of Betty Banner in a video game.
First appearance of Terraxia in a video game.
First (speaking) appearance of Adam Warlock in a video game.
First appearance of She-Hulk in a video game.
First appearance of Scarlet Witch in a video game.
First appearance of Eric Masterson Thor in a video game. (Despite in Cap's ending his dialogue is closer to actual Thor.)
Hardware / Consoles
It was the 14th game released on Capcom's CP System II (CPS-2) hardware in the arcades.
The title's debut is documented as October 24, 1995 for Asia and North America followed by releases in Japan (November 17, 1995) and Brazil (November 1995).
There have been (technically) 5 official home ports of the game.
Sega Saturn (1997 / Japan, North America, & Europe), Sony Playstation (1997 / Japan, North America, & Europe), Xbox Live and Playstation Network (2012 / in Marvel vs. Capcom Origins collection), and Arcade1Up cabinets (2021).
The Sega Saturn version was widely accepted as the better home console port during the late 1990s.
*This one was provided by DrFunk on X/Twitter who stated:
"The Saturn version was the first game to use a RAM cart in the US - and it wasn't even advertised"
Locations
First time Chaos Dimension was shown in a video game.
Chaos Dimension was the first Marvel stage that had no corner once wall breaks and would loop infinitely. (Wonder if it's the first Capcom stage that did that?)
First time Hell (or Mephisto's Realm) was shown in a video game.
First time Thanos' floating asteroid from the Infinity Gauntlet story was represented in a video game.
Even though character sprites were reused, none of the stage BGs from this title made appearances again in later installments.
(Even though similar locations appeared later, they were completely different.)
Story
The Infinity Gauntlet Saga
First time the gems and overall story was used as a plot in a video game.
(Original comic run by Jim Starlin, George Pérez, Ron Lim, Josef Rubinstein, Tom Christopher, Bruce N Solotoff,Jack Morelli, Max Scheele, Ian Laughlin, and Craig Anderson)
Extra Info
Infinity Gems were a whole new gameplay aspect at the time for a fighting game.
Only Marvel game to have Infinity Counters that work exactly like Alpha Counters.
Majority of the characters have infinites in this game (a potential unending combo) or OTD (one touch death combos) thanks to the combo system, gems, and the way the damage scales (or lax of the scaling).